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Rapid (R) plasma(P) reagin (R), is a blood test for syphilis that looks for an antibody that is present in the bloodstream when a patient has syphilis.

A negative (nonreactive) RPR is compatible with a person not having syphilis, but in the early stages of the disease, the RPR often gives false negative results. Conversely, a false positive RPR can be encountered in infectious mononucleosis, lupus, antiphospholipid antibody syndrome, hepatitis A, leprosy, malaria and, occasionally, pregnancy

 

 

  • many of the signs and symptoms are indistinguishable from those of other diseases.
  • always treatable but curable only if diagnosed early
  • sores also can occur on the lips and in the mouth.
  • if adequate treatment is not administered, the infection progresses to the secondary stage.
  • approximately 30,000 cases of syphilis in adults are reported each year in the United States.
  • the risk of transmission to the fetus in untreated primary or secondary syphilis is approximately 100%.
  • treatment is usually 100% effective and results in a cure with simple antibiotics from your neighborhood doctor.

 

 

 

What is syphilis?

 

Syphilis is a complex sexually transmitted disease (STD) caused by the bacterium Treponema pallidum. It has often been called "the great imitator" because so many of the signs and symptoms are indistinguishable from those of other diseases.

 

How is syphilis spread?

 

Syphilis is passed from person to person through direct contact with a syphilis sore. Sores occur mainly on the external genitals, vagina, anus, or in the rectum. Sores also can occur on the lips and in the mouth. Transmission of the organism occurs during vaginal, anal, or oral sex. Pregnant women with the disease can pass it to the babies they are carrying. Syphilis cannot be spread by toilet seats, door knobs, swimming pools, hot tubs, bath tubs, shared clothing, or eating utensils.

 

 

Signs and symptoms in adults?

 

 

Primary Stage:


The time between infection with syphilis and the start of the first symptom can range from 10-90 days (average 21 days). The primary stage of syphilis is usually marked by the appearance of a single sore (called a chancre), but there may be multiple sores. The chancre is usually firm, round, small, and painless. It appears at the spot where syphilis entered the body. The chancre lasts 3-6 weeks, and it will heal on its own. If adequate treatment is not administered, the infection progresses to the secondary stage.

 

Secondary Stage:


The second stage starts when one or more areas of the skin break into a rash that usually does not itch. Rashes can appear as the chancre is fading or can be delayed for weeks. The rash often appears as rough, red or reddish brown spots both on the palms of the hands and on the bottoms of the feet. The rash also may also appear on other parts of the body with different characteristics, some of which resemble other diseases. Sometimes the rashes are so faint that they are not noticed. Even without treatment, rashes clear up on their own. In addition to rashes, second-stage symptoms can include fever, swollen lymph glands, sore throat, patchy hair loss, headaches, weight loss, muscle aches, and tiredness. A person can easily pass the disease to sex partners when primary or secondary stage signs or symptoms are present.

 

 

Late Syphilis:


The latent (hidden) stage of syphilis begins when the secondary symptoms disappear. Without treatment, the infected person still has syphilis even though there are no signs or symptoms. It remains in the body, and it may begin to damage the internal organs, including the brain, nerves, eyes, heart, blood vessels, liver, bones, and joints. This internal damage may show up many years later in the late or tertiary stage of syphilis. Late stage signs and symptoms include not being able to coordinate muscle movements, paralysis, numbness, gradual blindness and dementia. This damage may be serious enough to cause death.

If the disease has not been effectively treated, bacteria can continue to invade the body, and there will be a relapse. In this phase, there is a widespread infection that infects the internal organs, bones, the heart, and the brain. Approximately 30,000 cases of syphilis in adults are reported each year in the United States. Congenital syphilis occurs in 1:10,000 live births. Transplacental (from mother to fetus) transmission of syphilis can result in stillbirth. The risk of transmission to the fetus in untreated primary or secondary syphilis is approximately 100%.

A blood test can determine whether someone has syphilis. Shortly after infection occurs, the body produces syphilis antibodies that can be detected by an accurate, safe and inexpensive blood test. A low level of antibodies will stay in the blood for months or years even after the disease has been successfully treated. Because untreated syphilis in a pregnant woman can infect and possibly kill her developing baby, every pregnant woman should have a blood test for syphilis

Treatment is usually 100% effective and results in a cure with simple antibiotics from your neighborhood doctor.

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